The name Alexandros is of Greek origin, derived from the Greek words "alexo" meaning "to defend" and "aner" meaning "man". It first appeared around the 4th century BC and was popularized by the legendary Macedonian king Alexander the Great, who lived from 356-323 BC and conquered the Persian Empire, establishing one of the largest empires in antiquity.

The name Alexandros appears in several ancient Greek texts, including the works of Homer, Plato, and Aristotle. It was a popular name among the Greek nobility and royalty, and it continued to be used throughout the Byzantine Empire and the Eastern Orthodox Church.

One of the earliest recorded examples of the name Alexandros is Alexander the Great himself. Born in 356 BC in Pella, the ancient capital of Macedonia, he became one of the most celebrated military leaders in history, conquering lands from Greece to India.

Another notable figure with the name Alexandros was Alexander of Aphrodisias, a Greek philosopher and commentator on Aristotle who lived in the late 2nd and early 3rd century AD. He made significant contributions to the study of Aristotelian philosophy and logic.

In the 4th century AD, Alexandros was the name of a Christian martyr from Thessalonica, who was executed during the reign of Emperor Maximian for refusing to renounce his faith. Saint Alexandros is venerated in the Eastern Orthodox Church and the Roman Catholic Church.

During the Byzantine Empire, several emperors bore the name Alexandros, including Alexandros I (912-913 AD) and Alexandros II (1285-1286 AD). Alexandros I was a co-emperor with his brother Leo VI, while Alexandros II was a short-lived ruler who was deposed and blinded.

In the 19th century, Alexandros Ypsilantis (1792-1828) was a prominent figure in the Greek War of Independence against the Ottoman Empire. He led the initial uprising in the Danubian Principalities, which helped spark the broader revolution in Greece.

Throughout history, the name Alexandros has been associated with strength, courage, and leadership, reflecting its Greek origins and the legacy of Alexander the Great.