Anastacia is a feminine given name with Greek origins, derived from the word "anastasis" meaning "resurrection" or "rising up." The name traces its roots back to the Byzantine Empire and the Eastern Orthodox Christian tradition.

The earliest recorded use of the name can be found in various hagiographies and accounts of Christian martyrs from the 3rd and 4th centuries. One notable early bearer was Saint Anastasia, a Roman martyr during the reign of Emperor Diocletian in the early 4th century. Her feast day is celebrated on December 25th in the Eastern Orthodox Church.

During the Middle Ages, the name gained popularity across the Eastern Mediterranean region, particularly in Greece, Cyprus, and parts of the Byzantine Empire. It was often bestowed upon girls as a symbol of faith and spiritual resilience.

In the 16th century, the name spread to other parts of Europe, including Russia, where it was adopted as Anastasiya. One of the most famous historical figures with this name was Anastasia Romanova, the youngest daughter of Tsar Nicholas II, who was tragically executed along with her family during the Russian Revolution in 1918.

Another notable bearer was Anastasia of Kiev, a 12th-century Grand Princess of Kyiv and the wife of King Andrew I of Hungary. She played a significant role in the Christianization of Hungary and is revered as a saint in the Eastern Orthodox Church.

In the literary world, the name gained recognition through the character of Anastasia Dualla in the reimagined Battlestar Galactica television series, which aired from 2004 to 2009.

Other historical figures bearing the name Anastacia include Anastasia Somoza, the wife of Nicaraguan dictator Anastasio Somoza García (1896-1956), and Anastasia Romanovna Zakharyna-Yuriev, a 16th-century Russian noblewoman and the first wife of Tsar Ivan IV "the Terrible" (1530-1584).