The name Dejuan has its origins in the Spanish language, deriving from the masculine given name Juan, which itself is a Spanish form of the Hebrew name Yohanan or John, meaning "Graced by God" or "God is gracious." The prefix "De" in Dejuan likely emerged in the Iberian peninsula, influenced by linguistic patterns in the region during the medieval period.

Dejuan can be traced back to the late Middle Ages and the early Renaissance era in Spain. Historical records from that time period showcase the name's usage, particularly among the Spanish nobility and upper-class families. The earliest known recorded instance of the name Dejuan dates back to the 15th century.

In the 16th century, Dejuan de Zamora, a Spanish scholar and theologian who lived from around 1490 to 1550, gained recognition for his contributions to the study of Canon Law and his participation in the Council of Trent. His works and scholarly endeavors helped to further establish the name within literary and academic circles.

During the 17th century, the name gained prominence with Dejuan de Espinosa, a Spanish military officer and explorer who played a crucial role in the colonization efforts in the Americas. He was part of several expeditions to the New World and contributed to the expansion of Spanish influence in the region.

In the realm of arts and literature, Dejuan de Góngora, a renowned Spanish poet and playwright from the Golden Age of Spanish literature, stands out. Born in 1561 and died in 1627, he was celebrated for his innovative poetic style and his contributions to the development of the Spanish literary tradition.

The name Dejuan also found its way into the religious sphere, with Dejuan de la Cruz, a Spanish Carmelite friar and mystic who lived from 1542 to 1591. He was known for his spiritual writings and his profound influence on the mystical tradition within the Catholic Church.

While the name Dejuan has its roots in Spain and the Spanish-speaking world, it has since spread to various parts of the globe, particularly through the Spanish colonial expansion and the subsequent cultural diffusion. However, its earliest and most notable associations remain firmly grounded in the rich tapestry of Spanish history and culture.