The name Dru has its origins in the ancient French language, derived from the Old French word "dru," meaning "hardy" or "vigorous." It emerged as a given name during the medieval period in France, around the 12th or 13th century.

The name Dru is believed to have been initially used as a nickname or descriptive term for someone who was physically strong or robust. Over time, it transitioned into a formal given name, particularly popular among the French nobility and upper classes.

One of the earliest recorded instances of the name Dru can be found in the 13th-century French epic poem "La Chanson de Roland," where it is mentioned as the name of a knight. This literary reference suggests that the name had already gained some recognition and usage during that era.

Throughout history, several notable individuals have borne the name Dru. One of the earliest was Dru de Melun (c. 1175 - c. 1234), a French nobleman and military leader who participated in the Fourth Crusade and the Albigensian Crusade. Another early figure was Dru Boutteville (c. 1595 - 1670), a French aristocrat and courtier during the reign of Louis XIII.

In the 19th century, Dru Drury (1725 - 1804) was an English entomologist and author of the influential work "Illustrations of Natural History." Additionally, Dru Gladney (1936 - 2022) was an American anthropologist and scholar of Chinese ethnic minorities, known for his expertise on the Uyghur people.

More recently, Dru Hill (formed in 1992) is the name of an American R&B vocal group, best known for their hit songs "In My Bed" and "How Deep Is Your Love." While the group's name is not directly related to the given name Dru, it has contributed to the name's recognition and contemporary usage.