The name Hadassah has its origins in the Hebrew language and culture. It is derived from the Hebrew word "hadas," which means "myrtle tree." The myrtle tree holds significant symbolism in Jewish tradition, representing beauty, fertility, and peace.

Hadassah is perhaps most famously associated with the biblical figure of Esther, whose Hebrew name was Hadassah. According to the Book of Esther in the Hebrew Bible, Hadassah was a young Jewish woman who became the Queen of Persia during the reign of King Ahasuerus. Her story is celebrated during the Jewish holiday of Purim, which commemorates her bravery and the deliverance of the Jewish people from persecution.

One of the earliest recorded individuals with the name Hadassah was Hadassah Bashi (1518-1568), a Jewish woman from the Ottoman Empire who was renowned for her philanthropy and support of Jewish education. Another notable figure was Hadassah Berachah Varnhagen (1805-1889), a German Jewish writer and salonnière who hosted intellectual gatherings and advocated for Jewish emancipation.

During the 20th century, Hadassah became a popular name among Jewish communities around the world, particularly in the United States. Hadassah Lieberman (born 1938) is a prominent American Jewish author and the wife of former U.S. Senator Joseph Lieberman. Hadassah Gurion (1917-2000) was the wife of David Ben-Gurion, the first Prime Minister of Israel, and played an active role in the establishment of the State of Israel.

Hadassah Froman (1921-2023) was an Israeli peace activist and founder of the Tent of Nations, a farm located in the West Bank that promotes coexistence and reconciliation between Israelis and Palestinians. She dedicated her life to promoting dialogue and understanding between different communities in the region.

Throughout its history, the name Hadassah has carried symbolic meanings of beauty, strength, and resilience, drawing from its biblical roots and the inspiring stories of remarkable women who have borne this name.