The given name Ilana has its origins in the Hebrew language. It is a feminine form derived from the Hebrew name Ilan, which means "tree" or "oak tree." The name has been in use since ancient times in the Middle Eastern region.

Ilana is mentioned in the Hebrew Bible, specifically in the Book of Samuel, as the name of one of King David's wives. This suggests that the name has been in use for at least 3,000 years.

One of the earliest recorded individuals with the name Ilana was Ilana Rama, a prominent Jewish scholar and philosopher who lived in the 10th century CE in present-day Iraq. She is known for her contributions to the fields of mathematics and astronomy.

In the 11th century, Ilana bat Judah was a noted poet and author who lived in Spain during the Golden Age of Jewish culture in the Iberian Peninsula. Her works were influential in the development of Hebrew literature.

During the Middle Ages, Ilana de Cardona was a influential figure in the court of the Kingdom of Aragon in the 13th century. She played a role in the political and cultural affairs of the time.

In more recent history, Ilana Trager was a Polish-Israeli writer and educator who lived from 1915 to 1996. She was a prominent figure in the development of Hebrew literature and education in Israel.

Another notable individual with the name Ilana was Ilana Yahav, an Israeli intelligence officer and military leader who served in the Israeli Defense Forces from the 1950s to the 1980s. She played a significant role in several military operations and was highly respected for her leadership and strategic abilities.