The name Jerome has its origins in the Greek name Hieronymus, which is derived from the elements "hieros" meaning sacred and "onoma" meaning name. It can be translated to mean "sacred name" or "holy name."

The name gained widespread recognition and popularity due to the 4th century scholar and priest, St. Jerome. Born around 347 AD in Stridon, a city on the border of Dalmatia and Pannonia, St. Jerome is best known for translating the Bible into Latin, a version known as the Vulgate.

One of the earliest recorded instances of the name Jerome can be found in the Bible, specifically in the Book of Ezra. Jerome is mentioned as a priest who participated in the dedication of the new wall of Jerusalem.

In the Middle Ages, the name Jerome became popular across Europe, particularly in regions influenced by the Catholic Church and the veneration of saints. It was commonly given to children as a way to honor St. Jerome and his contributions to Christianity.

Some notable historical figures named Jerome include St. Jerome (347-420 AD), the scholar and priest who translated the Bible into Latin; Jerome of Prague (1370-1416), a Czech philosopher and religious reformer; Jerome Kern (1885-1945), an American composer of musical theater; Jerome Robbins (1918-1998), an American choreographer and director; and Jerome K. Jerome (1859-1927), an English writer and humorist best known for the novel "Three Men in a Boat."

Throughout history, the name Jerome has been used across various cultures and regions, including Europe, North America, and parts of the Middle East. It has remained a popular choice for parents seeking a name with a strong religious and historical significance.