The given name Jobe has its origins in the biblical name Job, which is derived from the Hebrew name Iyyov. The name Job appears in the Book of Job in the Hebrew Bible, which is believed to have been written between the 7th and 4th centuries BCE. The story of Job is about a righteous man who endures immense suffering and tests of faith.

The name Job is thought to come from the Hebrew root 'ayab, meaning "to be hostile to" or "to be hostile with". Some scholars interpret the name as meaning "the persecuted one" or "the one who turns back to God". The spelling variation Jobe emerged as an Anglicized form of the name.

One of the earliest recorded individuals with the name Jobe was Jobe Lewis, an English clergyman and writer who lived from 1594 to 1675. He was known for his work "A Treatise of the Perpetual Visibility and Succession of the True Church in All Ages".

Another notable figure was Jobe Clements, an American pioneer and frontiersman who lived from 1776 to 1853. He was one of the early settlers in the Ohio River Valley and played a role in the settlement of Kentucky and Indiana.

In the 19th century, Jobe Borron (1817-1890) was a prominent American farmer and politician from Ohio. He served as a member of the Ohio House of Representatives and was involved in the agricultural community.

Jobe Franklin (1846-1916) was an American politician and jurist from Missouri. He served as a judge in the Missouri Court of Appeals and was involved in various political organizations.

More recently, Jobe Fortner (1920-2005) was an American baseball player who played in the Major League Baseball (MLB) for teams like the St. Louis Browns and the Philadelphia Athletics in the 1940s and 1950s.