The name Laquisha has its roots in African American culture and is believed to have originated in the latter half of the 20th century. While its precise etymology is uncertain, it is thought to be a blend of the French name Laquita and the English name Keisha.

Laquita itself is a diminutive form of the French name Laqueline, which is derived from the male name Jacques, the French form of James. The name James comes from the Hebrew name Jacob, meaning "supplanter" or "one who follows." Keisha, on the other hand, is a variant of the name Keisha, which has its origins in the Irish name Caiside, meaning "pure" or "chaste."

There are no known historical references or ancient texts that mention the name Laquisha specifically. However, the name's component parts, Laquita and Keisha, have been in use for centuries, albeit in different cultural contexts.

Some of the earliest recorded examples of individuals bearing the name Laquisha include Laquisha Lawson, an American basketball player born in 1977, and Laquisha Jones, an American track and field athlete born in 1979. Other notable individuals with the name Laquisha include Laquisha Pierre, an American basketball player born in 1984, Laquisha Campbell, an American basketball player born in 1988, and Laquisha Brown, an American basketball player born in 1990.

While the name Laquisha is relatively modern in its construction, it reflects the rich cultural diversity and naming traditions of various ethnic groups, blending elements from French, English, Irish, and African American heritage. Its popularity in recent decades highlights the ongoing evolution of naming practices and the influence of cultural fusion on modern naming conventions.