The given name Mikyas has its origins in the ancient Ge'ez language, which was the lingua franca of the Aksumite Empire in modern-day Eritrea and Ethiopia. The name is derived from the Ge'ez word "mekyas," which means "redeemer" or "savior." This linguistic connection suggests that the name may have had religious connotations in its early usage.

Mikyas can be traced back to the 4th century CE, when the Aksumite Empire was at its peak. The name appears in several ancient inscriptions and historical records from that era, indicating its popularity among the Aksumite nobility and clergy. One of the earliest documented individuals bearing this name was Mikyas, a prominent Aksumite general who led military campaigns against the Kingdom of Kush in the late 4th century.

In the 6th century, a notable figure named Mikyas served as the Patriarch of the Ethiopian Orthodox Tewahedo Church. His tenure as the spiritual leader of the church coincided with the reign of Emperor Kaleb, a pivotal figure in the spread of Christianity in the region. This association with religious leadership further cemented the name's connection to the Christian faith in the region.

During the medieval period, the name Mikyas continued to be used among the Ethiopian aristocracy and clergy. One of the most notable bearers of this name was Mikyas, a 14th-century Ethiopian monk and scholar who authored several influential religious texts. His works played a significant role in preserving and promoting the teachings of the Ethiopian Orthodox Church.

Another historical figure named Mikyas was a 16th-century Ethiopian nobleman and military leader who fought against the Ottoman Empire's attempts to conquer the region. His resistance efforts helped maintain the sovereignty of the Ethiopian Empire during a turbulent period of foreign invasions.

In more recent times, Mikyas has been a relatively uncommon name, but it has been carried by a few notable individuals. For example, Mikyas Shemelamu, an Ethiopian artist and painter born in the early 20th century, gained recognition for his vibrant depictions of traditional Ethiopian life and culture.

Throughout its long history, the name Mikyas has maintained a strong connection to the Ethiopian cultural and religious traditions. Its linguistic roots and historical associations have imbued it with a sense of spiritual significance and national pride, making it a cherished name within the Ethiopian community.