Misael is a given name with Hebrew origins, derived from the biblical name "Mishael". The name is composed of two elements: "mi" meaning "who" and "el" meaning "God", essentially translating to "who is like God". Its roots can be traced back to the Old Testament and the Book of Daniel.

The earliest recorded instance of the name Misael appears in the Book of Daniel, where it is one of the Hebrew names given to Daniel and his three companions upon their arrival in Babylon. Misael was the name bestowed upon Mishael, one of Daniel's friends, alongside Hananiah, Azariah, and Daniel himself.

Throughout history, several notable individuals have borne the name Misael. One of the earliest mentions is Misael, a 6th-century Byzantine scholar and theologian who authored commentaries on various biblical texts. In the 13th century, Misael was the name of a French composer and poet associated with the Franciscan order.

Another prominent figure bearing the name Misael was Misael Bañuelos (1872-1934), a Mexican bishop who served as the Bishop of Saltillo from 1923 until his death. He played a significant role in mediating tensions between the Catholic Church and the Mexican government during the Cristero War.

Misael Pastrana Borrero (1923-1997) was a Colombian politician and diplomat who served as the President of Colombia from 1970 to 1974. He was known for his efforts to promote economic development and social welfare programs during his tenure.

In the world of literature, Misael Arteaga (1909-1944) was a Panamanian poet and essayist who is considered one of the most influential figures in Panamanian literature. His works explored themes of nationalism, identity, and the struggles of the working class.

While the name Misael has Hebrew roots and biblical connections, it has been adopted and used across various cultures and time periods, with individuals bearing this name leaving their mark in fields ranging from religion and politics to literature and the arts.