The name Regina is a feminine given name that originates from the Latin word "regina," meaning "queen." Its roots can be traced back to the Roman Empire, where it was used to refer to the empress or the wife of the emperor.

Regina gained popularity during the Middle Ages, particularly in Catholic-dominated regions of Europe. It was often bestowed upon girls born into royal or noble families, reflecting their elevated status and the hope that they would grow up to become respected and influential women.

One of the earliest recorded instances of the name Regina can be found in the Biblical Book of Esther. In this text, Queen Esther is referred to as "Regina Esther" in the Latin translation. This association with a powerful and influential biblical figure contributed to the name's widespread use in Christian communities.

Throughout history, several notable figures have borne the name Regina. One of the most famous was Regina Margherita of Savoy (1851-1926), the Queen Consort of Italy from 1878 until her death. She was known for her charitable works and her support for the unification of Italy.

Another prominent Regina was Regina Maria Roche (1764-1845), an Irish writer and novelist best known for her Gothic novel "The Children of the Abbey," which was widely popular in the late 18th and early 19th centuries.

In the realm of music, Regina Spektor (born in 1980) is a Russian-American singer-songwriter and pianist who has gained critical acclaim for her unique blend of genres and her poetic lyrics.

The name Regina also has a strong connection to the Catholic Church. Saint Regina, also known as Saint Regina of Autun, was a 3rd-century Christian martyr who was venerated for her unwavering faith and courage in the face of persecution.

Additionally, Regina is the name of several cities and towns around the world, including Regina, the capital city of the Canadian province of Saskatchewan, and Regina, a town in the Piedmont region of Italy.

While the name Regina has maintained its popularity throughout the centuries, it has also seen variations and diminutives emerge, such as Rina, Gina, and Reine, which reflect the cultural and linguistic diversity of different regions.