The name Rena is a feminine given name with origins tracing back to ancient Greece and Latin. It derives from the Greek word "rhene," meaning "lamb" or "ewe." In Latin, the word "rena" means "kidney." The name was initially used as a pet form or diminutive of various Greek and Latin names containing the "ren" sound, such as Irene or Renata.

During the Middle Ages, the name Rena gained popularity across Europe, particularly in regions influenced by Greek and Latin cultures. It was commonly used in Italy, France, and other parts of Western Europe. The earliest recorded instances of the name date back to the 11th and 12th centuries, appearing in various historical documents and records.

One of the earliest known historical figures bearing the name Rena was Rena of Provins, a French mystic and anchoress who lived in the late 12th century. She was known for her spiritual visions and writings, which influenced religious thought during her time.

In the 13th century, Rena Burgundio, an Italian scholar and translator, made significant contributions to the translation of ancient Greek texts into Latin. Her work helped preserve and disseminate classical knowledge during the Renaissance period.

Another notable figure was Rena da Feltre, an Italian painter and illuminator active in the early 15th century. She is renowned for her intricate and beautifully illuminated manuscripts, which were highly prized by wealthy patrons.

In the 16th century, Rena Piccolomini, an Italian noblewoman and patron of the arts, played a significant role in supporting and promoting Renaissance artists and intellectuals. She was part of the influential Piccolomini family and was known for her patronage of Michelangelo and other luminaries of the era.

During the 17th century, Rena Molina, a Spanish playwright and poet, gained recognition for her literary works, which explored themes of love, passion, and societal norms. Her plays and poems were widely acclaimed and performed in her lifetime.

While the name Rena has maintained a presence throughout history, it has ebbed and flowed in popularity over time, often influenced by cultural trends and regional preferences. Today, it continues to be used as a feminine given name across various parts of the world, carrying the legacy of its ancient roots and historical significance.