The name Roxane has its origins in the ancient Greek language. It is derived from the Greek word "roxane" which means "bright" or "shining". This name was particularly popular in ancient Greece and the surrounding regions during the classical period, which spanned from the 5th to the 4th century BCE.

One of the earliest recorded examples of the name Roxane is from the play "The Persians" by the ancient Greek playwright Aeschylus, written in 472 BCE. In this tragedy, Roxane is mentioned as the daughter of a Persian king. The name also appears in several other ancient Greek texts and historical records from that era.

Perhaps the most famous historical figure bearing the name Roxane was the wife of Alexander the Great. Born in 340 BCE, Roxane was a Bactrian princess whom Alexander married in 327 BCE during his conquest of the Persian Empire. Their son, Alexander IV, was born after Alexander's death and became a short-lived king of the Macedonian Empire.

Another notable Roxane in ancient history was Roxane of Persia, who lived in the 3rd century BCE. She was the daughter of the Persian King Oxathres and was married to Alexander the Great's general, Crateros.

Moving forward in time, the name Roxane was also used during the Renaissance period in Europe. One example is Roxane de Lautrec, a French noblewoman who lived in the 16th century and was known for her beauty and intelligence.

In the 17th century, the name Roxane gained popularity in literature, particularly in the play "Bajazet" by the French playwright Jean Racine. The title character, Roxane, is a powerful and influential woman in the Ottoman Empire who becomes the object of desire for the Turkish sultan Bajazet.

Throughout history, the name Roxane has been associated with strong, intelligent, and sometimes controversial women. It has been used across various cultures and time periods, reflecting its enduring appeal and rich historical significance.