The given name Santos originates from the Latin language and the word "sanctus," meaning "holy" or "saintly." This name has its roots in early Christianity and was likely first used as a descriptive nickname or honorific for individuals who were regarded as particularly devout or virtuous.

In the early centuries of the Christian era, as the religion spread throughout the Roman Empire, the name Santos may have been bestowed upon those who dedicated their lives to the faith or achieved a level of spiritual reverence. It carried connotations of piety, righteousness, and a connection to the divine.

One of the earliest recorded instances of the name Santos can be found in the writings of the Church Fathers, who were influential Christian theologians and scholars from the 2nd to the 8th century. These texts often mentioned individuals with the name Santos, typically in the context of religious leadership or martyrdom.

As Christianity gained prominence, the name Santos became more widespread, particularly in regions with strong Catholic traditions, such as the Iberian Peninsula (Spain and Portugal) and parts of Latin America. The veneration of saints in these cultures further solidified the name's association with holiness and spirituality.

Throughout history, several notable individuals have borne the name Santos, including Santos Dumont (1873-1932), a Brazilian aviation pioneer renowned for his pioneering work in airship design and flight. Another prominent figure was Santos Inocentez (1900-1981), a Filipino poet and playwright whose works explored themes of nationalism and social justice.

In the 16th century, Santos Garcia (1542-1610), a Spanish Roman Catholic priest, gained recognition for his missionary work and efforts to convert indigenous populations in the Americas. Similarly, Santos Luzardo (1786-1868), a Venezuelan military leader and politician, played a significant role in the country's struggle for independence.

The name Santos has also been associated with religious figures, such as Santos Marmolejo (1535-1592), a Spanish Dominican friar and missionary who introduced Christianity to parts of Central America. His legacy as a pioneering evangelist and defender of indigenous rights earned him widespread respect.