The name Sargon is of Akkadian origin, an extinct Semitic language that was spoken in ancient Mesopotamia during the late Bronze Age. The name is believed to derive from the Akkadian word "sharru," meaning "king" or "ruler." It is first recorded in ancient cuneiform texts from the 24th century BC, referring to Sargon of Akkad, one of the earliest and most famous rulers of Mesopotamia.

Sargon of Akkad, also known as Sargon the Great, was the founder of the Akkadian Empire and is considered one of the world's first great empire-builders. He reigned from around 2334 to 2279 BC and is known for his military conquests, as well as his administrative and cultural reforms. The name Sargon became closely associated with his legacy and is mentioned in various ancient texts, including the Sumerian King List and the inscriptions of his grandson, Naram-Sin.

In addition to Sargon of Akkad, the name was also used by several other historical figures in the ancient Near East. One notable example is Sargon II, a king of the Neo-Assyrian Empire who ruled from 722 to 705 BC. He was known for his military campaigns, as well as his ambitious building projects, including the construction of the city of Khorsabad.

Another famous bearer of the name was Sargon of Sidon, a Phoenician ruler who lived in the 8th century BC. He is mentioned in the Assyrian records of Sargon II and is believed to have been a vassal or ally of the Assyrian Empire.

In the Bible, the name Sargon appears in the Book of Isaiah, referring to an Assyrian king who conquered the kingdom of Israel. While some scholars debate whether this refers to Sargon II or another Assyrian ruler, the name's inclusion in the biblical text highlights its significance in the ancient Near East.

Other notable individuals named Sargon include Sargon of Awan (6th century BC), a ruler of the ancient kingdom of Awan in modern-day Iran, and Sargon of Assyria (8th century BC), a king of the Neo-Assyrian Empire who is mentioned in the Assyrian royal inscriptions.