The name Serene originated from the Latin word "serenus" which means "clear, calm, or unruffled." It entered the English language as an adjective in the late 16th century, and its use as a given name didn't become popular until much later.

One of the earliest known references to the name Serene can be found in John Milton's epic poem "Paradise Lost," published in 1667. In Book IV, Milton describes the serene atmosphere of the Garden of Eden, using the word as an adjective to convey a sense of tranquility and peace.

The first recorded use of Serene as a given name dates back to the early 19th century. One of the earliest known individuals with this name was Serene Harriet Amelia Greville (1819-1848), an English noblewoman and lady-in-waiting to Queen Victoria.

Throughout history, several notable individuals have borne the name Serene. One of the most famous was Serene Jones (1919-2002), an American author and playwright who wrote several children's books and plays, including the popular work "The Eye of the Needle."

Another prominent figure named Serene was Serene Khader (1933-2016), a Jordanian diplomat and the first woman to serve as an ambassador from Jordan. She played a significant role in promoting women's rights and education in the Middle East.

In the literary world, Serene Abadee (1942-2021) was a renowned Jordanian poet and writer who published numerous collections of poetry and novels. Her works explored themes of love, identity, and the human experience.

Serene Nahas (1980-present) is a contemporary Lebanese-American artist and sculptor known for her large-scale installations and public art projects. Her works often explore the relationship between nature, technology, and the human experience.

While the name Serene may have originated from a Latin word, its use as a given name has transcended cultural and geographical boundaries, with notable individuals bearing this name across various regions and time periods.