The name Tyana is believed to have originated from the ancient Greek language. It is derived from the word "tyana," which means "lady" or "mistress." The name first appeared in the region of Anatolia, which is now modern-day Turkey, during the Hellenic period around the 4th century BC.

Tyana was a city located in the ancient Kingdom of Cappadocia, and it was known for its rich cultural heritage and historical significance. The city was mentioned in several ancient texts, including the works of the Greek philosopher and historian Strabo, who lived between 64 BC and 24 AD.

One of the earliest recorded examples of the name Tyana was Apollonius of Tyana, a renowned Neopythagorean philosopher and miracle worker who lived in the 1st century AD. He was known for his great wisdom and his ability to perform miraculous feats, and his life was documented by several ancient writers, including Philostratus.

Another notable figure with the name Tyana was Saint Tyana, a Christian martyr who lived in the 3rd century AD. She was born in Tyana and was eventually executed for her Christian beliefs during the reign of the Roman Emperor Diocletian.

In the medieval period, the name Tyana was also associated with a legendary figure known as the Lady of Tyana. According to local folklore, she was a beautiful and powerful sorceress who lived in the city of Tyana and was said to possess magical abilities.

During the Renaissance, the name Tyana was popularized by the Italian poet and playwright Ludovico Ariosto, who featured a character named Tyana in his epic poem "Orlando Furioso," written in the early 16th century.

Other notable figures with the name Tyana throughout history include Tyana Wachter (1907-1971), a German actress and dancer; Tyana Parry (1902-1972), a British actress and singer; and Tyana Vego (born 1980), a Croatian model and TV presenter.